Article
Epigenetic biomarkers in esophageal cancer.
Cancer letters - 28 Jan 2014
Kaz Andrew M, Grady William M
Abstract excerpt
The aberrant DNA methylation of tumor suppressor genes is well documented in esophageal cancer, including adenocarcinoma (EAC) and squamous cell carcinoma (ESCC) as well as in Barrett's esophagus (BE), a pre-malignant condition that is associated with chronic acid reflux. BE is a well-recognized risk factor for the development of EAC, and consequently the standard of care is for individuals with BE to be placed...
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