Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Characteristics of Basaloid Squamous Cell Carcinoma of the Esophagus: Analysis of KRAS, BRAF, and PIK3CA Mutations and LINE-1 Methylation.

Annals of surgical oncology - 1 Oct 2015

Baba Yoshifumi, Ishimoto Takatsugu, Harada Kazuto, Kosumi Keisuke, Murata Asuka, Miyake Keisuke, Hiyoshi Yukiharu, Kurashige Junji, Iwatsuki Masaaki, Iwagami Shiro, Miyamoto Yuji, Sakamoto Yasuo, Yoshida Naoya, Oki Eiji, Iyama Ken-Ichi, Watanabe Masayuki, Baba Hideo

Abstract excerpt

BACKGROUND: Basaloid squamous cell carcinoma (BSCC) of the esophagus is a rare carcinoma with distinct characteristics, and was recently recognized as a variant of squamous cell carcinoma (SCC). We previously revealed genetic and epigenetic alterations associated with esophageal SCCs in relation to clinical outcome, including mutations in KRAS, BRAF, and PIK3CA, p53 expression, and long interspersed nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Class I Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

Share to Long Interspersed Nucleotide Elements

Share to Phosphatidylinositol 3-Kinases

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins p21(ras)

Share to Survival Rate

Source

Identifiers

PMID: 25691283
DOI: 10.1245/s10434-015-4445-z

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Characteristics of Basaloid Squamous Cell Carcinoma of the Esophagus: Analysis of KRAS, BRAF, and PIK3CA Mutations and LINE-1 Methylation.PMID 25691283Read ↗

Integrated molecular characterization of esophageal basaloid squamous cell carcinoma: a subtype with distinct RNA expression pattern and immune characteristics, but no specific genetic mutations.Semantic proximity Read ↗

Clinicopathological and mutational analysis of esophageal basaloid squamous cell carcinoma.Semantic proximity Read ↗

Aberrant DNA Methylation in Esophageal Squamous Cell Carcinoma: Biological and Clinical ImplicationsSemantic proximity Read ↗

Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma.Semantic proximity Read ↗

Racial Differences in Esophageal Squamous Cell Carcinoma: Incidence and Molecular FeaturesSemantic proximity Read ↗

Molecular pathology and potential therapeutic targets in esophageal basaloid squamous cell carcinoma.Semantic proximity Read ↗

Genomic and Epigenomic Aberrations in Esophageal Squamous Cell Carcinoma and Implications for Patients.Semantic proximity Read ↗

Immunohistochemical and oncogenetic analyses of the esophageal basaloid squamous cell carcinoma in comparison with conventional squamous cell carcinomas.Semantic proximity Read ↗

Characterization of epigenetic alterations in esophageal cancer by whole-genome bisulfite sequencingSemantic proximity Read ↗

Somatic mutations of esophageal adenocarcinoma: a comparison between Black and White patientsSemantic proximity Read ↗

The genomic landscape of small cell carcinoma of the esophagusSemantic proximity Read ↗

Targeted bisulfite sequencing identified a panel of DNA methylation-based biomarkers for esophageal squamous cell carcinoma (ESCC)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.