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Article

A role for the 30S subunit E site in maintenance of the translational reading frame.

RNA (New York, N.Y.) - 1 Feb 2009

Devaraj Aishwarya, Shoji Shinichiro, Holbrook Eric D, Fredrick Kurt

Abstract excerpt

The exit (E) site has been implicated in several ribosomal activities, including translocation, decoding, and maintenance of the translational reading frame. Here, we target the 30S subunit E site by introducing a deletion in rpsG that truncates the beta-hairpin of ribosomal protein S7. This mutation (S7DeltaR77-Y84) increases both -1 and +1 frameshifting but does not increase miscoding, providing evidence that...

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Topics

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Share to Amino Acid Sequence
Share to Escherichia coli
Share to Frameshifting, Ribosomal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Open Reading Frames

Share to Peptide Elongation Factor G

Share to Protein Structure, Secondary

Share to Protein Transport

Source

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Identifiers

PMID: 19095617
DOI: 10.1261/rna.1320109
PMCID: PMC2648707

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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