Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetics in Sjögren Syndrome.

Rheumatic diseases clinics of North America - 1 Aug 2016

Reksten Tove Ragna, Lessard Christopher J, Sivils Kathy L

Abstract excerpt

The genes associated with Sjögren syndrome (SS) can be assigned to the NF-kB pathway, the IFN signaling pathway, lymphocyte signaling, and antigen presentation. The frequencies of risk variants show they are common with modest genetic effects. The strongest genetic association outside the human leukocyte antigen region is in IRF5, a gene relevant in the IFN signaling pathway and for B cell differentiation....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to Interferon Regulatory Factors
Share to Interleukins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Sjogren's Syndrome

Share to src-Family Kinases

Share to STAT4 Transcription Factor

Share to Tumor Necrosis Factor alpha-Induced Protein 3

Share to Vascular Cell Adhesion Molecule-1

Source

Identifiers

PMID: 27431346
DOI: 10.1016/j.rdc.2016.03.003

Genes

TNFAIP3
TNIP1
VCAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetics in Sjögren Syndrome.PMID 27431346Read ↗

Contribution of Genetic Factors to Sjögren's Syndrome and Sjögren's Syndrome Related Lymphomagenesis.Semantic proximity Read ↗

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.Semantic proximity Read ↗

Genetics of Sjögren's syndrome.Semantic proximity Read ↗

Genetics and epigenetics in primary Sjögren’s syndromeSemantic proximity Read ↗

Genetics of Sjögren's syndrome in the genome-wide association era.Semantic proximity Read ↗

Genetics and genomics of Sjögren's syndrome: research provides clues to pathogenesis and novel therapies.Semantic proximity Read ↗

Interferons in Sjögren’s Syndrome: Genes, Mechanisms, and EffectsSemantic proximity Read ↗

Uncovering potential single nucleotide polymorphisms, copy number variations and related signaling pathways in primary Sjogren's syndrome.Semantic proximity Read ↗

Genes and Sjögren's syndrome.Semantic proximity Read ↗

Variants at potential loci associated with Sjogren's syndrome in Koreans: A genetic association study.Semantic proximity Read ↗

Sjogren's syndrome: Everything you always wanted to know about genetic and epigenetic factors.Semantic proximity Read ↗

Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.