Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of cytotoxic T lymphocyte associated antigen-4 gene (rs60872763) polymorphism with Crohn's disease and high levels of serum sCTLA-4 in Crohn's disease.

Journal of gastroenterology and hepatology - 1 May 2011

Chen Zhitao, Zhou Feng, Huang Sha, Jiang Ting, Chen Liping, Ge Liuqing, Xia Bing

Abstract excerpt

BACKGROUND AND AIM: Our aim was to evaluate cytotoxic T lymphocyte associated antigen-4 (CTLA-4) gene polymorphisms in Crohn's disease (CD) and explore soluble CTLA-4 (sCTLA-4) levels in serum of CD patients in central China. METHODS: A total of 126 Chinese CD patients and 300 healthy controls were enrolled in this study. CTLA-4 (AT)n repeat polymorphism was genotyped by a semiautomatic fluorescently labeled...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Antigens, CD

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to C-Reactive Protein

Share to Chi-Square Distribution

Share to Crohn Disease

Share to CTLA-4 Antigen

Share to Enzyme-Linked Immunosorbent Assay

Share to Nephelometry and Turbidimetry

Source

Identifiers

PMID: 21251066
DOI: 10.1111/j.1440-1746.2011.06662.x

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of cytotoxic T lymphocyte associated antigen-4 gene (rs60872763) polymorphism with Crohn's disease and high levels of serum sCTLA-4 in Crohn's disease.PMID 21251066Read ↗

Correlation Between IL-8 Gene Polymorphisms and Pathogenesis of Crohn's Disease.Semantic proximity Read ↗

CTLA4 -1661A/G and 3'UTR long repeat polymorphisms are associated with ulcerative colitis and influence CTLA4 mRNA and protein expression.Semantic proximity Read ↗

Association between STAT3 gene polymorphisms and Crohn's disease susceptibility: a case-control study in a Chinese Han population.Semantic proximity Read ↗

CTLA4 CT60 single-nucleotide polymorphism is associated with Slovenian inflammatory bowel disease patients and regulates expression of CTLA4 isoforms.Semantic proximity Read ↗

CTLA-4 polymorphisms and susceptibility to inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

Cytotoxic T lymphocyte antigen-4 promoter -658CT gene polymorphism is associated with ulcerative colitis in Chinese patients.Semantic proximity Read ↗

[CTLA-4 gene polymorphism regulates CTLA-4 mRNA stability and protein level in patients with ulcerative colitis].Semantic proximity Read ↗

The epidemiology and phenotype of Crohn's disease in the Chinese population.Semantic proximity Read ↗

Association of polymorphic alleles of CTLA4 with inflammatory bowel disease in the Japanese.Semantic proximity Read ↗

Association of intestinal granulomas with smoking, phenotype, and serology in Chinese patients with Crohn's disease.Semantic proximity Read ↗

Polymorphisms of the TNF Gene and Three Susceptibility Loci Are Associated with Crohn's Disease and Perianal Fistula Crohn's Disease: A Study among the Han Population from South China.Semantic proximity Read ↗

[Association of ITGA4 and ICAM-1 gene polymorphisms with the risk and clinicopathological characteristics of Crohn's disease].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.