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Article

Polymorphisms in the interleukin-10 gene cluster are possibly involved in the increased risk for major depressive disorder.

BMC medical genetics - 16 Dec 2008

Traks Tanel, Koido Kati, Eller Triin, Maron Eduard, Kingo Külli, Vasar Veiko, Vasar Eero, Kõks Sulev

Abstract excerpt

BACKGROUND: Innate immune inflammatory response is suggested to have a role in the pathogenesis of major depressive disorder (MDD). Interleukin (IL)-10 family cytokines IL-10, IL-19, IL-20, and IL-24 are all implicated in the inflammatory processes and polymorphisms in respective genes have been associated with various immunopathological conditions. This study was carried out to investigate whether...

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Identifiers

PMID: 19087313
DOI: 10.1186/1471-2350-9-111
PMCID: PMC2648955

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