Article
Interleukin 10 family gene polymorphisms are not associated with major depressive disorder and panic disorder phenotypes.
Journal of psychiatric research - 1 Apr 2010
Koido Kati, Eller Triin, Kingo Külli, Kõks Sulev, Traks Tanel, Shlik Jakov, Vasar Veiko, Vasar Eero, Maron Eduard
Abstract excerpt
Genetic regulation of immune system and inflammatory response may be related to the pathogenesis and manifestations of mood and anxiety disorders. In the present study we examined a range of single-nucleotide polymorphisms (SNP) in chromosomal region 1q32, the locus of interleukin 10 (IL10) gene, in patients with major depressive disorder (n=312) and panic disorder (n=210), and matched healthy controls (n=356)....
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