Article
Polybromo-1: the chromatin targeting subunit of the PBAF complex.
Biochimie - 1 Mar 2009
Thompson Martin
Abstract excerpt
The human Polybromo-1 protein (Pb1) was recently identified as a unique subunit of the PBAF (Polybromo, Brg1-Associated Factors) chromatin-remodeling complex required for kinetochore localization during mitosis and the transcription of estrogen-responsive genes. Pb1 coordinates key features common to all remodeling complexes, including chromatin localization, recruitment of protein subunits and alteration of...
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