Article
Ki-ras oncogene mutations in chronic pancreatitis: which discriminating ability for malignant potential?
Annals of the New York Academy of Sciences - 30 Jun 1999
van Laethem J L
Abstract excerpt
Ki-ras mutations are found in the majority of pancreatic adenocarcinomas (85-100%). Ki-ras analysis was increasingly used in ERCP samples in order to differentiate between chronic pancreatitis and pancreatic cancer. However, its sensitivity was recently reported to be low due to a high prevalence of ras mutations in patients with chronic pancreatitis (25-37%). Detection of Ki-ras mutations in microdissected...
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