Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[The relevance of leukotriene C(4) synthase gene A (-444) C polymorphism to clinical responsiveness to montelukast in patients with asthma].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases - 1 Nov 2008

Wu Yong-Hong, Liu Chun-Tao, Wang Ke, Geng Yan-Ming

Abstract excerpt

OBJECTIVE: To investigate the frequency of leukotriene C(4) synthase gene A (LTC(4)S A) -444 C polymorphism in asthmatics of Chinese Han nationality in Southwest China and to evaluate its relevance to clinical responsiveness to leukotriene receptor antagonist. METHODS: A hundred and fifty asthmatics and 146 healthy blood donors were recruited. The genotype distribution of A/C polymorphism of LTC(4)S A(-444)C gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetates
Share to Anti-Asthmatic Agents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Asthma

Share to Cyclopropanes

Share to Glutathione Transferase

Share to Quinolines

Share to Sulfides

Share to Treatment Outcome

Source

Identifiers

PMID: 19080532

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[The relevance of leukotriene C(4) synthase gene A (-444) C polymorphism to clinical responsiveness to montelukast in patients with asthma].PMID 19080532Read ↗

[Association of leukotriene gene polymorphisms with response to antileukotriene treatment in patients with asthma].Semantic proximity Read ↗

The -444A/C polymorphism in the LTC4S gene and the risk of asthma: a meta-analysis.Semantic proximity Read ↗

Association between leukotriene C4 synthase A-444C polymorphism and asthma in Chinese Han population in Beijing.Semantic proximity Read ↗

Polymorphisms of the PTGDR and LTC4S influence responsiveness to leukotriene receptor antagonists in Korean children with asthma.Semantic proximity Read ↗

Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT(1) antagonist, pranlukast, in Japanese patients with moderate asthma.Semantic proximity Read ↗

The A-444C polymorphism in the leukotriene C4 synthase gene is associated with aspirin-induced urticaria.Semantic proximity Read ↗

Influence of leukotriene pathway polymorphisms on clinical responses to montelukast in Japanese patients with asthma.Semantic proximity Read ↗

Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma.Semantic proximity Read ↗

Association of the -1072G/A polymorphism in the LTC4S gene with asthma in an Indian population.Semantic proximity Read ↗

Analysis of 927T > C CYSLTR1 and -444A > C LTC4S polymorphisms in children with asthma.Semantic proximity Read ↗

Analysis of 927T> C CYSLTRI and -444A > C LTC4S polymorphisms in patients with asthma.Semantic proximity Read ↗

Lack of an association between a newly identified promoter polymorphism (-1702G > A) of the leukotriene C4 synthase gene and aspirin-intolerant asthma in a Korean population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.