Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial and Nuclear Cross Talk in Cell Death

1 Dec 2008

Abstract excerpt

Poly(ADP-ribose) polymerase-1 (PARP-1) is an abundant nuclear protein best known to facilitate DNA base excision repair. Recent work has expanded the physiologic functions of PARP-1, and it is clear that the full range of biologic actions of this important protein are not yet fully understood. Regulation of the product of PARP-1, poly(ADP-ribose) (PAR), is a dynamic process with PAR glycohydrolase playing the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell death mechanisms and regulation
Share to Integrated Circuits and Semiconductor Failure Analysis
Share to PARP inhibition in cancer therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19076445
DOI: 10.1196/annals.1427.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial and Nuclear Cross Talk in Cell DeathPMID 19076445Read ↗

Parthanatos: mitochondrial‐linked mechanisms and therapeutic opportunitiesSemantic proximity Read ↗

Parthanatos, a messenger of deathSemantic proximity Read ↗

Poly (ADP-Ribose) polymerase 1 and parthanatos in neurological diseases: From pathogenesis to therapeutic opportunitiesSemantic proximity Read ↗

Poly (ADP-ribose) in the pathogenesis of Parkinson's diseaseSemantic proximity Read ↗

Pharmacologic inhibition of MIF nuclease: A new treatment paradigm to treat cell deathSemantic proximity Read ↗

Emerging role of PARP‐1 and PARthanatos in ischemic strokeSemantic proximity Read ↗

Beyond DNA Repair: Additional Functions of PARP-1 in CancerSemantic proximity Read ↗

Exploring the role of parthanatos in CNS injury: Molecular insights and therapeutic approachesSemantic proximity Read ↗

Histone H1.2 Dependent Translocation of Poly (ADP-ribose) Initiates ParthanatosSemantic proximity Read ↗

PARP1: Liaison of Chromatin Remodeling and TranscriptionSemantic proximity Read ↗

PARP (Poly ADP‐ribose Polymerase) Family in Health and DiseaseSemantic proximity Read ↗

A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.