Article
Culture characters, genetic background, estrogen/progesterone receptor expression, and tumorigenic activities of frequently used sixteen endometrial cancer cell lines.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2019
Qu Wanglei, Zhao Yinling, Wang Xuan, Qi Yaozhi, Zhou Clare, Hua Ying, Hou Jianqing, Jiang Shi-Wen
Abstract excerpt
BACKGROUND: This study aimed to determine the in vitro and in vivo properties of sixteen frequently used endometrial cancer (EC) cell lines, including the cell proliferation rate, morphology, hormone receptor expression patterns, PTEN, hMLH1 expression, p53 mutation, karyotype, and tumorigenicity in mouse xenograt model. METHODS: Twelve type I (AN3, ECC-1, EN, EN-1, EN-11, HEC-1A, HEC1B, Ishikawa, KLE, MFE-280,...
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