Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toll-like receptor 4 gene polymorphism downregulates gene expression and involves in susceptibility to bladder cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2015

Shen Yizhen, Bu Meimei, Zhang Aimin, Liu Yi, Fu Baochen

Abstract excerpt

Bladder cancer is the ninth most frequent malignancy in China. Toll-like receptor 4 (TLR4) is expressed on various cells and greatly involves in immune responses. Genetic polymorphism may affect the pathogenesis of diseases through various pathways. In the current study, we evaluated the association between genetic polymorphisms in TLR4 and risk of bladder cancer. We also examined the effect of the polymorphisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to CD8-Positive T-Lymphocytes

Share to Gene Expression Regulation, Neoplastic

Share to Toll-Like Receptor 4

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 25472584
DOI: 10.1007/s13277-014-2902-0

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toll-like receptor 4 gene polymorphism downregulates gene expression and involves in susceptibility to bladder cancer.PMID 25472584Read ↗

Toll-like receptor 4 gene polymorphisms and susceptibility to bladder cancer.Semantic proximity Read ↗

729G/C polymorphism in Toll-like receptor 4 results in increased susceptibility to bladder cancer.Semantic proximity Read ↗

Single-nucleotide polymorphisms in genes encoding toll-like receptor -2, -3, -4, and -9 in a case-control study with bladder cancer susceptibility in a North Indian population.Semantic proximity Read ↗

Association detection between genetic variants in the microRNA binding sites of toll-like receptors signaling pathway genes and bladder cancer susceptibility.Semantic proximity Read ↗

Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.Semantic proximity Read ↗

Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms in cancer: a meta-analysis.Semantic proximity Read ↗

The TLR4 gene polymorphisms and susceptibility to cancer: a systematic review and meta-analysis.Semantic proximity Read ↗

Impact of Toll-like receptor 4 polymorphisms on risk of cancer.Semantic proximity Read ↗

-196 to -174del, rs4696480, rs3804099 polymorphisms of Toll-like receptor 2 gene impact the susceptibility of cancers: evidence from 37053 subjects.Semantic proximity Read ↗

Differential Expression of the TLR4 Gene in Pan-Cancer and Its Related MechanismSemantic proximity Read ↗

Association of Toll-like 4 receptor gene polymorphism (rs4986790, rs4986791) with the risk of urinary tract infection: A systematic review and meta-analysis.Semantic proximity Read ↗

Role of toll-like receptor 4 in colorectal carcinogenesis: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.