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Article

EGFR pathway polymorphisms and bladder cancer susceptibility and prognosis.

Carcinogenesis - 1 Jul 2009

Mason Rebecca A, Morlock Elaine V, Karagas Margaret R, Kelsey Karl T, Marsit Carmen J, Schned Alan R, Andrew Angeline S

Abstract excerpt

The epidermal growth factor receptor (EGFR) pathway has recently been appreciated as a central mediator of tumorigenesis and an important drug target; however, the influence of genetic variation in this pathway on bladder cancer is not understood. Pathway activation leads to cell proliferation, angiogenesis and is antiapoptotic. We sought to test the hypothesis that bladder cancer susceptibility and survival are...

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Source

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Identifiers

PMID: 19372140
DOI: 10.1093/carcin/bgp077
PMCID: PMC2704279

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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