Article
Toll-like receptor 4 gene polymorphisms and susceptibility to bladder cancer.
Pathology oncology research : POR - 1 Apr 2013
Shen Yizhen, Liu Yi, Liu Shaoge, Zhang Aimin
Abstract excerpt
Bladder cancer is one of the most common malignancies in the world. Toll-like receptor 4 (TLR4) plays important roles in regulating innate immunity and may affect the development of cancers. Polymorphisms in TLR4 gene have been shown to be associated with impaired immune responses. Here, we investigated the association of TLR4 polymorphisms with bladder cancer. Four TLR4 polymorphisms (-2242T/C, Asp299Gly,...
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