Article
HSD3B and gene-gene interactions in a pathway-based analysis of genetic susceptibility to bladder cancer.
PloS one - 1 Jan 2012
Andrew Angeline S, Hu Ting, Gu Jian, Gui Jiang, Ye Yuanqing, Marsit Carmen J, Kelsey Karl T, Schned Alan R, Tanyos Sam A, Pendleton Eben M, Mason Rebecca A, Morlock Elaine V, Zens Michael S, Li Zhongze, Moore Jason H, Wu Xifeng, Karagas Margaret R
Abstract excerpt
Bladder cancer is the 4(th) most common cancer among men in the U.S. We analyzed variant genotypes hypothesized to modify major biological processes involved in bladder carcinogenesis, including hormone regulation, apoptosis, DNA repair, immune surveillance, metabolism, proliferation, and telomere maintenance. Logistic regression was used to assess the relationship between genetic variation affecting these...
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