Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional ERRgamma2-mediated activation is regulated by sentrin-specific proteases.

The Biochemical journal - 1 Apr 2009

Hentschke Moritz, Süsens Ute, Borgmeyer Uwe

Abstract excerpt

Modification with SUMOs (small ubiquitin-related modifiers) has emerged as an important means of regulating the activity of transcription factors, often by repressing their activity. The ERRgamma [oestrogen receptor-related receptor gamma; ERR3 or NR3B3 (nuclear receptor subfamily 3, group B, gene3)] is a constitutively active orphan nuclear receptor. A PDSM, (phosphorylation-dependent sumoylation motif) is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cysteine Endopeptidases
Share to Electrophoretic Mobility Shift Assay

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Multienzyme Complexes

Share to Phosphorylation

Share to Receptors, Estrogen

Share to Small Ubiquitin-Related Modifier Proteins

Share to Transcription, Genetic

Share to Transcriptional Activation

Source

Identifiers

PMID: 19067653
DOI: 10.1042/BJ20081556

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional ERRgamma2-mediated activation is regulated by sentrin-specific proteases.PMID 19067653Read ↗

Sentrin/SUMO specific proteases as novel tissue-selective modulators of vitamin D receptor-mediated signaling.Semantic proximity Read ↗

Sumoylation: a regulatory protein modification in health and disease.Semantic proximity Read ↗

Ligand binding reduces SUMOylation of the peroxisome proliferator-activated receptor γ (PPARγ) activation function 1 (AF1) domain.Semantic proximity Read ↗

SUMOylation of RORalpha potentiates transcriptional activation function.Semantic proximity Read ↗

Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma.Semantic proximity Read ↗

Post-Translational Modifications of Nuclear Receptors and Human DiseaseSemantic proximity Read ↗

The Inhibitory Function in Human Progesterone Receptor N Termini Binds SUMO-1 Protein to Regulate Autoinhibition and TransrepressionSemantic proximity Read ↗

A CK2-RNF4 interplay coordinates non-canonical SUMOylation and degradation of nuclear receptor FXR.Semantic proximity Read ↗

Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity.Semantic proximity Read ↗

Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation.Semantic proximity Read ↗

The DEAD-box protein DP103 (Ddx20 or Gemin-3) represses orphan nuclear receptor activity via SUMO modification.Semantic proximity Read ↗

Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.