Article
HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy.
Genome research - 1 Mar 2009
Friedrichs Frauke, Zugck Christian, Rauch Gerd-Jörg, Ivandic Boris, Weichenhan Dieter, Müller-Bardorff Margit, Meder Benjamin, El Mokhtari Nour Eddine, Regitz-Zagrosek Vera, Hetzer Roland, Schäfer Arne, Schreiber Stefan, Chen Jian, Neuhaus Isaac, Ji Ruiru, Siemers Nathan O, Frey Norbert, Rottbauer Wolfgang, Katus Hugo A, Stoll Monika
Abstract excerpt
Human dilated cardiomyopathy (DCM), a disorder of the cardiac muscle, causes considerable morbidity and mortality and is one of the major causes of sudden cardiac death. Genetic factors play a role in the etiology and pathogenesis of DCM. Disease-associated genetic variations identified to date have been identified in single families or single sporadic patients and explain a minority of the etiology of DCM. We...
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