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Article

Alteration of the substrate specificity of the angular dioxygenase carbazole 1,9a-dioxygenase.

Bioscience, biotechnology, and biochemistry - 1 Dec 2008

Uchimura Hiromasa, Horisaki Tadafumi, Umeda Takashi, Noguchi Haruko, Usami Yusuke, Li Li, Terada Tohru, Nakamura Shugo, Shimizu Kentaro, Takemura Tetsuo, Habe Hiroshi, Furihata Kazuo, Omori Toshio, Yamane Hisakazu, Nojiri Hideaki

Abstract excerpt

Carbazole 1,9a-dioxygenase (CARDO) consists of terminal oxygenase (CARDO-O) and electron transport components. CARDO can catalyze specific oxygenation for various substrates: angular dioxygenation for carbazole and dibenzo-p-dioxin, lateral dioxygenation for anthracene, and monooxygenation for methylene carbon of fluorene and sulfide sulfur of dibenzothiophene. To elucidate the molecular mechanism determining its...

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Identifiers

PMID: 19060398
DOI: 10.1271/bbb.80512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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