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Article

Insights into the binding interaction of substrate with catechol 2,3-dioxygenase from biophysics point of view.

Journal of hazardous materials - 5 Jun 2020

Zeng Xian-Hong, Du Huan, Zhao Hai-Ming, Xiang Lei, Feng Nai-Xian, Li Hui, Li Yan-Wen, Cai Quan-Ying, Mo Ce-Hui, Wong Ming-Hung, He Zhen-Li

Abstract excerpt

This study aims to clarify the interaction mechanism of substrate with catechol 2,3-dioxygenase (C23O) through multi-technique combination. A novel C23O (named C23O-2G) was cloned, heterogeneously expressed, and identified as a new member in subfamily I.2 of extradiol dioxygenases. Based on the simulations of molecular docking and dynamics, the exact binding sites of catechol on C23O-2G were identified, and the...

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Identifiers

PMID: 32036315
DOI: 10.1016/j.jhazmat.2020.122211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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