Article
Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders.
Biological psychiatry - 1 Jun 2009
Goldstein Inbal, Lerer Elad, Laiba Efrat, Mallet Jacques, Mujaheed Mustafa, Laurent Claudine, Rosen Haim, Ebstein Richard P, Lichtstein David
Abstract excerpt
BACKGROUND: The sodium- and potassium-activated adenosine triphosphatase (Na+, K+-ATPase) is a major plasma membrane transporter for sodium and potassium. We recently suggested that bipolar disorders (BD) may be associated with alterations in brain Na+, K+-ATPase. We further conjectured that the differences in Na+, K+-ATPase in BD patients could result partially from genetic variations in Na+, K+-ATPase alpha...
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