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Article

Bir1 is required for the tension checkpoint.

Molecular biology of the cell - 1 Feb 2009

Shimogawa Michelle M, Widlund Per O, Riffle Michael, Ess Michael, Davis Trisha N

Abstract excerpt

The Saccharomyces cerevisiae chromosomal passenger proteins Ipl1 (Aurora B) and Sli15 (INCENP) are required for the tension checkpoint, but the role of the third passenger, Bir1, is controversial. We have isolated a temperature-sensitive mutant (bir1-107) in the essential C-terminal region of Bir1 known to be required for binding to Sli15. This allele reveals a checkpoint function for Bir1. The mutant displays a...

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Source

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Identifiers

PMID: 19056681
DOI: 10.1091/mbc.e08-07-0723
PMCID: PMC2633401

Genes

INCENP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Bir1 is required for the tension checkpoint.PMID 19056681Read ↗

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