Article
A globally occurring indel polymorphism in the promoter of the IFNA2 gene is not associated with severity of malaria but with the positivity rate of HCV.
BMC genetics - 3 Dec 2008
Tena-Tomás Cristina, de Messias-Reason Iara, Song Le H, Tomiuk Jürgen, Kemsner Peter G, Kun Jürgen F J
Abstract excerpt
BACKGROUND: Type I Interferons (IFNs) are well known cytokines which exert antiviral activity, antitumor activity and immunomodulatory effects. Single-nucleotide polymorphisms (SNP) and deletions in the gene coding for IFNA2 have been shown to influence the level of expression in vitro. The indel...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.