Article
Highly specific gene silencing by artificial microRNAs in the unicellular alga Chlamydomonas reinhardtii.
The Plant journal : for cell and molecular biology - 1 Apr 2009
Molnar Attila, Bassett Andrew, Thuenemann Eva, Schwach Frank, Karkare Shantanu, Ossowski Stephan, Weigel Detlef, Baulcombe David
Abstract excerpt
MicroRNAs (miRNAs) are small RNAs, 21 to 22 nucleotides long, with important regulatory roles. They are processed from longer RNA molecules with imperfectly matched foldback regions and they function in modulating the stability and translation of mRNA. Recently, we and others have demonstrated that the unicellular alga Chlamydomonas reinhardtii, like diverse multicellular organisms, contains miRNAs. These RNAs...
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