Article
Diversification of the core RNA interference machinery in Chlamydomonas reinhardtii and the role of DCL1 in transposon silencing.
Genetics - 1 May 2008
Casas-Mollano J Armando, Rohr Jennifer, Kim Eun-Jeong, Balassa Eniko, van Dijk Karin, Cerutti Heriberto
Abstract excerpt
Small RNA-guided gene silencing is an evolutionarily conserved process that operates by a variety of molecular mechanisms. In multicellular eukaryotes, the core components of RNA-mediated silencing have significantly expanded and diversified, resulting in partly distinct pathways for the epigenetic control of gene expression and genomic parasites. In contrast, many unicellular organisms with small nuclear genomes...
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