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Article

Most microRNAs in the single-cell alga Chlamydomonas reinhardtii are produced by Dicer-like 3-mediated cleavage of introns and untranslated regions of coding RNAs.

Genome research - 1 Apr 2016

Valli Adrian A, Santos Bruno A C M, Hnatova Silvia, Bassett Andrew R, Molnar Attila, Chung Betty Y, Baulcombe David C

Abstract excerpt

We describe here a forward genetic screen to investigate the biogenesis, mode of action, and biological function of miRNA-mediated RNA silencing in the model algal species,Chlamydomonas reinhardtii Among the mutants from this screen, there were three at Dicer-like 3 that failed to produce both miRNAs and siRNAs and others affecting diverse post-biogenesis stages of miRNA-mediated silencing. The DCL3-dependent...

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Identifiers

PMID: 26968199
DOI: 10.1101/gr.199703.115
PMCID: PMC4817775

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Source receipt: pubmed, retrieved 7 Sept 2026.

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