Article
An ortholog of the Vasa intronic gene is required for small RNA-mediated translation repression in Chlamydomonas reinhardtii.
Proceedings of the National Academy of Sciences of the United States of America - 7 Jan 2020
Ma Xinrong, Ibrahim Fadia, Kim Eun-Jeong, Shaver Scott, Becker James, Razvi Fareha, Cerny Ronald L, Cerutti Heriberto
Abstract excerpt
Small RNAs (sRNAs) associate with Argonaute (AGO) proteins in effector complexes, termed RNA-induced silencing complexes (RISCs), which regulate complementary transcripts by translation inhibition and/or RNA degradation. In the unicellular alga Chlamydomonas, several metazoans, and land plants, emerging evidence indicates that polyribosome-associated transcripts can be translationally repressed by RISCs without...
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