Article
Highly sensitive and specific multiplexed microRNA quantification using size-coded ligation chain reaction.
Analytical chemistry - 21 Jan 2014
Zhang Pengbo, Zhang Jiangyan, Wang Chengli, Liu Chenghui, Wang Hui, Li Zhengping
Abstract excerpt
As important regulators of gene expression, microRNAs (miRNAs) are emerging as novel biomarkers with powerful predictive value in diagnosis and prognosis for several diseases, especially for cancers. There is a great demand for flexible multiplexed miRNA quantification methods that can quantify very low levels of miRNA targets with high specificity. For further analysis of miRNA signatures in biological samples,...
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