Article
Association study between a functional glutathione S-transferase (GSTP1) gene polymorphism (Ile105Val) and tardive dyskinesia.
Neuroscience letters - 11 Nov 2005
Shinkai Takahiro, De Luca Vincenzo, Hwang Rudi, Matsumoto Chima, Hori Hiroko, Ohmori Osamu, Remington Gary, Meltzer Herbert Y, Lieberman Jeffrey A, Potkin Steven G, Nakamura Jun, Kennedy James L
Abstract excerpt
A possible role for oxidative stress in the pathophysiology of tardive dyskinesia (TD) has previously been proposed (reviewed in Andreassen and Jorgensen [O.A. Andreassen, H.A. Jorgensen, Neurotoxicity associated with neuroleptic-induced oral dyskinesias in rats Implications for tardive dyskinesia? Prog. Neurobiol. 61 (2000) 525-541]). Long-term administration of antipsychotics alters dopaminergic turnover, which...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
