Article
Uncoupling of the patterns of chromatin association of different transcription elongation factors by a histone H3 mutant in Saccharomyces cerevisiae.
Eukaryotic cell - 1 Feb 2009
Lloyd Amanda, Pratt Katie, Siebrasse Erica, Moran Matthew D, Duina Andrea A
Abstract excerpt
The transcription elongation complexes yFACT, Spt4/Spt5, and Spt6/Iws1 were previously shown to follow similar patterns of association across transcribed genes in Saccharomyces cerevisiae. Using a histone H3 mutant, we now provide evidence that the mechanism of association of yFACT across genes is separable from that adopted by Spt4/Spt5 and Spt6/Iws1.
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