Article
HLA-A33 is associated with susceptibility to enterovirus 71 infection.
Pediatrics - 1 Dec 2008
Chang Luan-Yin, Chang I-Shou, Chen Wei-Jen, Huang Yhu-Cherng, Chen Guang-Wu, Shih Shin-Ru, Juang Jyh-Lyh, Shih Hsiu-Ming, Hsiung Chao A, Lin Tzou-Yien, Huang Lin-Min
Abstract excerpt
OBJECTIVE: Enterovirus 71 has caused large epidemics of disease, resulting in many fatalities and severe sequelae, in Taiwan and some other countries. In this study, host genetic factors were investigated to link susceptibility to and clinical severity of enterovirus 71 infections. METHODS: We enrolled 219 enterovirus 71 case subjects and 97 control children. HLA typing was performed with sequence-specific...
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