Article
The variations of VP1 protein might be associated with nervous system symptoms caused by enterovirus 71 infection.
BMC infectious diseases - 7 May 2014
Zhang Bao, Wu Xianbo, Huang Keyong, Li Ling, Zheng Li, Wan Chengsong, He Ming-Liang, Zhao Wei
Abstract excerpt
BACKGROUND: The VP1 protein of enterovirus 71 (EV71) is an important immunodominant protein which is responsible for host-receptor binding. Nevertheless, the relationship between VP1 and neurovirulence is still poorly understood. In this study, we investigated the relationship between mutation of VP1 and neurovirulent phenotype of EV71 infection. METHODS: One hundred and eighty-seven strains from Genbank were...
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