Article
Role of the myb-like protein bas1p in Saccharomyces cerevisiae: a proteome analysis.
Molecular microbiology - 1 Nov 1998
Denis V, Boucherie H, Monribot C, Daignan-Fornier B
Abstract excerpt
The effect of extracellular adenine and the role of the transcriptional activator Bas1p on expression of the yeast genome was assessed by two-dimensional (2D) analysis of the yeast proteome. These data combined with LacZ fusions and northern blot analysis allow us to show that synthesis of enzymes for all 10 steps involved in purine de novo synthesis is repressed in the presence of adenine and requires BAS1 and...
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