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Article

Association of a polymorphism in the intron 7 of the SREBF1 gene with osteonecrosis of the femoral head in Koreans.

Annals of human genetics - 1 Jan 2009

Lee H-J, Choi S-J, Hong J M, Lee W K, Baek J-I, Kim S-Y, Park E K, Kim S-Y, Kim T-H, Kim U-K

Abstract excerpt

Reduction or disruption of the blood supply to the bone is involved in the pathogenesis of osteonecrosis of the femoral head (ONFH). An altered lipid metabolism is one of the major risk factors for ONFH. Sterol regulatory element binding protein, SREBF1 activates genes regulating lipid biosynthesis. The aim of this study was to examine the association between the polymorphisms of the SREBF1 gene and ONFH...

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Identifiers

PMID: 19040658
DOI: 10.1111/j.1469-1809.2008.00490.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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