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The relationship between genetic polymorphisms in apolipoprotein E (ApoE) gene and osteonecrosis of the femoral head induced by steroid in Chinese Han population.

Genes & genomics - 1 Feb 2018

Yuan Lin, Li Wei, Wang Xianquan, Yang Guang, Yu Haiyang, Sun Shui

Abstract excerpt

Previous studies suggested that apolipoprotein E (ApoE) genetic polymorphisms (SNPs) may result in abnormal lipid metabolism. Therefore, genetic polymorphisms in ApoE may be associated with the occurrence of osteonecrosis of the femoral head (ONFH). A case control study was designed to include 580 patients with steroid-induced ONFH and 560 age- and sex-matched non steroid-induced ONFH control subjects to analyze...

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Identifiers

PMID: 29892926
DOI: 10.1007/s13258-017-0625-5

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