Article
Association of gene variants of transcription factors PPARγ, RUNX2, Osterix genes and COL2A1, IGFBP3 genes with the development of osteonecrosis of the femoral head in Chinese population.
Bone - 1 Aug 2017
Song Yang, Du Zhenwu, Ren Ming, Yang Qiwei, Wang Qingyu, Chen Gaoyang, Zhao Haiyue, Li Zhaoyan, Wang Jincheng, Zhang Guizhen
Abstract excerpt
The molecular pathogenesis of osteonecrosis of the femoral head (ONFH) has been remained obscure so that its prevalence has been increasing in recent decades. Different transcription factors play critical roles in maintaining the balance between osteogenesis and adipogenesis. However, it has been unclear that the genes variants of the transcription factors exert the effects on the imbalance between steogenesis...
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