Article
Osteoprotegerin polymorphisms are associated with alcohol-induced osteonecrosis of femoral head in Chinese Han population from Henan province.
Journal of genetics - 1 Dec 2016
Li Yizhou, Guo Yongchang, Wang Quanjian, Ouyang Yongri, Cao Yuju, Jin Tianbo, Wang Jianzhong
Abstract excerpt
Alcohol-induced osteonecrosis of femoral head (ONFH) is one of the most important pathogenesis of nontraumatic ONFH. However, its pathogenesis mechanism is still unknown. Osteoprotegerin (OPG) has been implicated in multiple functions including blocking osteoclast maturation, controlling vascular calcifications, promoting tumour growth and metastasis. This study is focussed on OPG gene polymorphisms associated...
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