Article
Association of a polymorphism in PON-1 gene with steroid-induced osteonecrosis of femoral head in Chinese Han population.
Diagnostic pathology - 8 Nov 2013
Wang Zhiyao, Zhang Yanqiong, Kong Xiangying, Li Shangzhu, Hu Yimin, Wang Rongtian, Li Yan, Lu Chao, Lin Na, Chen Weiheng
Abstract excerpt
BACKGROUND: Treatment with steroids covers a wide spectrum of diseases in clinic. However, some users are suffering from serious side effects of steroid administration, while we enjoy the benefit it brings about. Osteonecrosis of the femoral head (ONFH) is a troublesome one among them. Recent studies have demonstrated that lipid metabolism disorder may play a vital role in pathogenesis of ONFH and mutation of the...
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