Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Poor Embryo Development in Mouse Oocytes Aged In Vitro Is Associated with Impaired Calcium Homeostasis1

27 Nov 2008

Abstract excerpt

We examined whether impairment of intracellular Ca(2+) homeostasis is related to poor embryo development in in vitro-aged oocytes. We found that in vitro aging of mouse oocytes affected the patterns of Ca(2+) oscillations at fertilization: these Ca(2+) oscillations were lower in amplitude and higher in frequency compared with oocytes without in vitro aging. We also observed that the intracellular Ca(2+) store was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian function and disorders
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19038861
DOI: 10.1095/biolreprod.108.072017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Poor Embryo Development in Mouse Oocytes Aged In Vitro Is Associated with Impaired Calcium Homeostasis1PMID 19038861Read ↗

Injection of Sperm Cytosolic Factor Into Mouse Metaphase II Oocytes Induces Different Developmental Fates According to the Frequency of [Ca2+]i Oscillations and Oocyte Age1Semantic proximity Read ↗

Mechanisms underlying oocyte activation and postovulatory ageingSemantic proximity Read ↗

Poor embryo development in post-ovulatory <i>in vivo</i> -aged mouse oocytes is associated with mitochondrial dysfunction, but mitochondrial transfer from somatic cells is not sufficient for rejuvenationSemantic proximity Read ↗

Melatonin Prevents Postovulatory Oocyte Aging in the Mouse and Extends the Window for Optimal Fertilization In Vitro1Semantic proximity Read ↗

Oocyte cryopreservation and in vitro culture affect calcium signalling during human fertilizationSemantic proximity Read ↗

Insufficiency of melatonin in follicular fluid is a reversible cause for advanced maternal age-related aneuploidy in oocytesSemantic proximity Read ↗

Dithiothreitol prevents age-associated decrease in oocyte/conceptus viability in vitroSemantic proximity Read ↗

Cumulus cells are required for the increased apoptotic potential in oocytes of aged miceSemantic proximity Read ↗

Restraint stress of female mice during oocyte development facilitates oocyte postovulatory agingSemantic proximity Read ↗

Rapamycin improves the quality and developmental competence of in vitro matured oocytes in aged mice and humansSemantic proximity Read ↗

CaV3.2 T-type channels mediate Ca2+ entry during oocyte maturation and following fertilizationSemantic proximity Read ↗

Ovary and ovulation: DNA fragmentation of oocytes in aged miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.