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Oocyte cryopreservation and in vitro culture affect calcium signalling during human fertilization

11 Nov 2013

Abstract excerpt

STUDY QUESTION: What are the precise patterns of calcium oscillations during the fertilization of human oocytes matured either in vivo or in vitro or aged in vitro and what is the effect of cryopreservation? SUMMARY ANSWER: Human oocytes matured in vivo exhibit a specific pattern of calcium oscillations, which is affected by in vitro maturation, in vitro ageing and cryopreservation. WHAT IS KNOWN ALREADY:...

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PMID: 24218403
DOI: 10.1093/humrep/det404

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