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Article

Ovary and ovulation: DNA fragmentation of oocytes in aged mice

1 Jul 1996

Abstract excerpt

To investigate whether female fertility decreases with age due to poor oocyte quality, we examined the presence of DNA fragmentation in ovulated oocytes from young, mature and aged mice. Oocytes from three age groups of female mice (7-8, 20-24 and 40-48 weeks) were retrieved from the oviducts 15 h after human chorionic gonadotrophin (HCG) injection. Oocytes from each mouse were incubated in a CO2 incubator for...

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PMID: 8671488
DOI: 10.1093/oxfordjournals.humrep.a019421

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