Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapamycin improves the quality and developmental competence of in vitro matured oocytes in aged mice and humans

26 Nov 2022

Abstract excerpt

Women over age 35 suffer from the inadequate number and poor quality of oocytes during assisted reproductive treatment, and making full use of the oocytes by in vitro maturation (IVM) is crucial. Rapamycin could improve the developmental competences of the post-maturation oocytes during in vitro aging, yet its effects on the IVM process of oocytes from an aged population were not clear. In this study, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian function and disorders
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36441531
DOI: 10.18632/aging.204401

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapamycin improves the quality and developmental competence of in vitro matured oocytes in aged mice and humansPMID 36441531Read ↗

Oocyte aging: cellular and molecular changes, developmental potential and reversal possibilitySemantic proximity Read ↗

Rapamycin improves the developmental competence of human oocytes by alleviating DNA damage during IVMSemantic proximity Read ↗

Control of mitochondrial integrity influences oocyte quality during reproductive agingSemantic proximity Read ↗

Growth hormone reduces aneuploidy and improves oocytes quality by JAK2-MAPK3/1 pathway in aged miceSemantic proximity Read ↗

Insufficiency of melatonin in follicular fluid is a reversible cause for advanced maternal age-related aneuploidy in oocytesSemantic proximity Read ↗

Oocyte aging underlies female reproductive aging: biological mechanisms and therapeutic strategiesSemantic proximity Read ↗

C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagySemantic proximity Read ↗

C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagySemantic proximity Read ↗

C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagySemantic proximity Read ↗

Effects of n-3 PUFA supplementation on oocyte in vitro maturation in mice with polycystic ovary syndromeSemantic proximity Read ↗

The Antioxidant Auraptene Improves Aged Oocyte Quality and Embryo Development in MiceSemantic proximity Read ↗

Oocyte quality and agingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.