Melatonin Prevents Postovulatory Oocyte Aging in the Mouse and Extends the Window for Optimal Fertilization In Vitro1

Abstract excerpt

The quality of metaphase II oocytes deteriorates rapidly following ovulation as the result of an aging process associated with impaired fertilizing potential, disrupted developmental competence, and increased likelihood of embryonic resorption. Because oxidative stress accelerates the onset of apoptosis in oocytes and influences their capacity for fertilization, this study aimed to characterize the significance...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Circadian rhythm and melatonin
• Share to Ovarian function and disorders
• Share to Reproductive Biology and Fertility