Article
Genome-wide transcriptomic and proteomic analysis of the primary response to phosphate limitation in Streptomyces coelicolor M145 and in a DeltaphoP mutant.
Proteomics - 1 Jul 2007
Rodríguez-García Antonio, Barreiro Carlos, Santos-Beneit Fernando, Sola-Landa Alberto, Martín Juan F
Abstract excerpt
Phosphate limitation in Streptomyces and in other bacteria triggers expression changes of a large number of genes. This response is mediated by the two-component PhoR-PhoP system. A Streptomyces coelicolor DeltaphoP mutant (lacking phoP) has been obtained by gene replacement. A genome-wide analysis of the primary response to phosphate limitation using transcriptomic and proteomic studies has been made in the...
Topics
- Amino Acids
- Cell Membrane Structures
- Gene Expression Profiling
- Genetic Vectors
- Genome, Bacterial
- Genomics
- Glucose
- Mutation
- Nitrogen
- Nucleotides
- Oxidative Stress
- Phosphates
- Promoter Regions, Genetic
- Proteins