Article
Assembly of the mitochondrial Tim9-Tim10 complex: a multi-step reaction with novel intermediates.
Journal of molecular biology - 4 Jan 2008
Ivanova Ekaterina, Jowitt Thomas A, Lu Hui
Abstract excerpt
Protein assembly is a crucial process in biology, because most proteins must assemble into complexes to perform their function in the cell. The mitochondrial Tim9-Tim10 translocase complex, located in the mitochondrial intermembrane space, plays an essential chaperone-like role during the import of mitochondrial membrane proteins. The complex consists of three molecules of each subunit arranged alternately in a...
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