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Article

Benign Nodal Nevi Frequently Harbor the Activating V600E BRAF Mutation

1 Apr 2009

Abstract excerpt

Mutational activation of the BRAF oncogene is the most common genetic alteration in cutaneous melanoma. Potentially, BRAF mutation analysis of sentinel lymph node (SLN) biopsies could enhance the detection of micrometastases and improve the accuracy of nodal staging for patients with melanoma. Nodal nevi are small aggregates of benign nevus cells that are commonly encountered in the SLNs of patients with...

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Share to Cutaneous Melanoma Detection and Management
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PMID: 19033861
DOI: 10.1097/pas.0b013e31818a64fb

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