Article
BRAF mutation screening in melanoma: is sentinel lymph node reliable?
Melanoma research - 1 Aug 2015
Nardin Charlée, Puzenat Eve, Prétet Jean Luc, Algros Marie Paule, Doussot Alexandre, Puyraveau Marc, Mougin Christiane, Aubin François
Abstract excerpt
As the detection of the BRAF V600E mutation has a direct impact on treatment decision, an accurate screening for BRAF mutations in patients with advanced or metastatic melanoma is mandatory. Nevertheless, BRAF oncogene mutation status between different samples from the same patient has been studied with conflicting results. This study investigated the intrapatient homogeneity of BRAF mutation status using...
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