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Article

Highly efficient JFH1-based cell-culture system for hepatitis C virus genotype 5a: failure of homologous neutralizing-antibody treatment to control infection.

The Journal of infectious diseases - 15 Dec 2008

Jensen Tanja B, Gottwein Judith M, Scheel Troels K H, Hoegh Anne M, Eugen-Olsen Jesper, Bukh Jens

Abstract excerpt

BACKGROUND: Recently, a hepatitis C virus (HCV) cell-culture system was developed that employed strain JFH1 (genotype 2a), and JFH1-based intra- and intergenotypic recombinants now permit functional studies of the structural genes (Core, E1, and E2), p7, and NS2 of genotypes 1-4. The goal was to adapt the system to employ genotype 5. METHODS: Huh7.5 cells infected with SA13/JFH1, containing Core-NS2 of strain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19032070
DOI: 10.1086/593021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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