Article
[Association between tumor necrosis factor alpha gene polymorphism and colorectal cancer].
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery - 1 Nov 2008
Wu Guo-yang, Wang Xiao-min, Keese Michael, Hasenberg Till, Sturm Jörg W
Abstract excerpt
OBJECTIVE: To elucidate the association of TNF-alpha-308G/A gene functional polymorphism with the development and progression of colorectal cancer. METHODS: PCR-RFLP was employed to detect the TNF-alpha-308 G/A genotypes in 157 colorectal cancer patients and 117 healthy controls. RESULTS: The frequency of TNF-alpha-308 genotype and allele were not significantly different between colorectal cancer patients and...
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