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Article

Polymorphisms of tumor necrosis factor alpha in Middle Eastern population with colorectal cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2016

Hamadien Maha-Abdulla, Khan Zahid, Vaali-Mohammed Mansoor-Ali, Zubaidi Ahmad, Al-Khayal Khayal, McKerrow James, Al-Obeed Omar

Abstract excerpt

Tumor necrosis factor-alpha (TNF-α) contributes in inflammation and has been implicated in the development of colorectal cancer (CRC). Single nucleotide polymorphisms (SNPs) in TNF-α promoter could affect the risk of CRC by regulating TNF-α production. This is the first study to investigate TNF-α SNPs in a Middle Eastern population. In this study, we examined three SNPs in TNF-α for association with CRC. One...

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PMID: 26572151
DOI: 10.1007/s13277-015-4421-z
PMCID: PMC4844627

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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